Avian Antibodies (IgY)-A New Weapon against Antibiotic Resistance
نویسنده
چکیده
Alternatives to antibiotics for the treatment and prevention of infections are badly needed. Passive immune therapy with avian antibodies (immune globulin, IgY) from eggs of hens, that have been vaccinated with a specific microbe, is a real alternative.
منابع مشابه
Avian Egg Yolk Antibodies (IgY) and their Potential Therapeutic Applications for Countering Infectious Diseases of Fish and Aquatic Animals
In the current scenario of increasing and emerging drug resistance in various microbial pathogens, traditional antibiotics are becoming less effective and thus globally research has focused on developing alternative therapeutic regimens having efficient germ killing abilities. The leading alternatives include use of phages, prebiotics, probiotics, cytokines, avian egg yolk antibodies, toll like...
متن کاملIgY Antibodies for the Prevention and Treatment of Helicobacter pylori Infections
Major progress has been made both in the field of vaccination and also in therapies against H. pylori infections in recent years. But, the increasing number of H. pylori infections and its resistance to current antibiotics has become a worldwide problem, due to the direct correlation between H. pylori infections and gastritis, gastric ulcers as well as cancer. In this regard, new alternative th...
متن کاملSpecificity of Chicken (IgY) versus Rabbit (IgG) Antibodies Raised against Cholecystokinin Octapeptide (CCK-8).
Antibodies produced in chickens (egg yolk Antibody-IgY) and rabbits against CCK-8 TyrSE (a C-terminal extended CCK-version) were compared with respect to their specificity against several modified CCK-sequences by means of radioimmunoassay and spot blot assay. The content of neuronal CCK was determined by using both an "avian" and a "mammalian" RIA. The IC50 values obtained indicate differences...
متن کاملProduction of Specific Egg Yolk Antibody (IgY) against Cryptosporidium parvum Oocysts
ABSTRACT Background and Objectives: Cryptosporidium parvum is a coccidian protozoan that causes diarrhea in immunocompromised humans and newborn animals. The severity of the disease depends on the immunological status of the affected. Cryptosporiosis can have lethal effects on immunocompromised individuals such as AIDS patients. About 10% of...
متن کاملCharacterization of IgY antibodies, developed in hens, directed against camel immunoglobulins
Chicken egg yolk antibodies (IgY) against camel immunoglobulins were generated and their specificity was shown by double immunodiffusion, immunoelectrophoresis, and Western blotting. Anti camel antibodies specifically react to camel antibodies in immunodiffusion and immunoelectrophoresis were demonstrated. Western blotting revealed that IgY antibodies recognize the heavy chain in a number of ma...
متن کامل